Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | BCL9 | O00512 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9539549 | 0.94 | ALDH1A1 (0.47) | ALDH1A1KDM4EPOLBMEN1KMT2A | |
| SCHEMBL9540713 | 0.87 | USP2 (0.57) | ALDH1A1KDM4EPOLBL3MBTL1PKM | |
| SCHEMBL9540756 | 0.82 | ALDH1A1 (0.51) | ALDH1A1KDM4EPOLBMEN1KMT2A | |
| SCHEMBL9540760 | 0.82 | ALDH1A1 (0.51) | ALDH1A1KDM4EPOLBMEN1KMT2A | |
| SCHEMBL9542165 | 0.81 | KDM4E (0.56) | KDM4EPOLBMEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL9542211 | 0.80 | ALDH1A1 (0.47) | ALDH1A1KDM4EPOLBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9539440 | 0.80 | AURKA (0.50) | ALDH1A1KDM4EPOLBMEN1KMT2A | |
| SCHEMBL9539532 | 0.78 | MAPT (0.58) | ALDH1A1KDM4EPOLBMEN1KMT2A | |
| SCHEMBL28369269 | 0.77 | MEN1 (0.53) | ALDH1A1KDM4EPOLBMEN1KMT2A | |
| SCHEMBL9539607 | 0.77 | MAPT (0.56) | ALDH1A1KDM4EPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993005054-A1 | OXAZAPHOSPHORINES USEFUL AS ANTITUMOR AGENTS, A PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1993-03-18 | — | — | WO | disclosed |