Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9539459 | 0.94 | ALDH1A1 (0.48) | ALDH1A1KDM4EPOLBHTTLMNA | |
| Hydrochloric Acid SCHEMBL9539426 | 0.86 | USP2 (0.55) | ALDH1A1KDM4EPOLBHTTLMNA | |
| SCHEMBL9539438 | 0.85 | ELANE (0.48) | ALDH1A1KDM4EPOLBMEN1KMT2A | |
| SCHEMBL9539623 | 0.82 | ALDH1A1 (0.52) | ALDH1A1KDM4EPOLBHTTMAPT | |
| SCHEMBL9540788 | 0.81 | KDM4E (0.55) | ALDH1A1KDM4EPOLBHTTLMNA | |
| SCHEMBL9538718 | 0.79 | ELANE (0.48) | ALDH1A1KDM4EPOLBHTTLMNA | |
| Hydrochloric Acid SCHEMBL9542188 | 0.78 | ELANE (0.47) | ALDH1A1KDM4EPOLBHTTLMNA | |
| Hydrochloric Acid SCHEMBL9540795 | 0.78 | ELANE (0.47) | ALDH1A1KDM4EPOLBHTTLMNA | |
| SCHEMBL9542191 | 0.77 | MAOA (0.53) | ALDH1A1KDM4EHTTLMNAMAPT | |
| SCHEMBL9539549 | 0.76 | ALDH1A1 (0.47) | ALDH1A1KDM4EPOLBHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993005054-A1 | OXAZAPHOSPHORINES USEFUL AS ANTITUMOR AGENTS, A PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1993-03-18 | — | — | WO | disclosed |