Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 11/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 11/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.35 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.34 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5734673 | 0.93 | SLC6A3 (0.43) | SLC6A2SLC6A4SLC6A3P2RX7MEN1 | |
| SCHEMBL20902343 | 0.86 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3P2RX7FFAR1 | |
| SCHEMBL20902391 | 0.84 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3FPR2PROKR1 | |
| SCHEMBL20446557 | 0.79 | FFAR1 (0.35) | SLC6A2SLC6A4SLC6A3FFAR1LMNA | |
| SCHEMBL9539582 | 0.78 | RPS6KB1 (0.39) | FFAR1 | |
| SCHEMBL6907975 | 0.76 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3P2RX7FFAR1 | |
| SCHEMBL7705768 | 0.76 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3P2RX7FFAR1 | |
| SCHEMBL9643779 | 0.76 | SLC6A4 (0.47) | SLC6A2SLC6A4SLC6A3P2RX7FFAR1 | |
| SCHEMBL6917685 | 0.76 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3P2RX7FFAR1 | |
| SCHEMBL27820014 | 0.76 | SLC6A4 (0.47) | SLC6A2SLC6A4SLC6A3P2RX7FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5223536-A | Pyrethroid-like pesticides | FMC CORPORATION (US) | 1993-06-29 | — | — | US | disclosed |
| WO-1993001715-A1 | 1,4-DIARYL-1-CYCLOPROPYL-4-SUBSTITUTED BUTANES AS INSECTICIDES AND ACARICIDES | FMC CORPORATION (US) | 1993-02-04 | — | — | WO | disclosed |