Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 11/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9539663 | 0.78 | SLC1A3 (0.57) | ALOX5ALDH1A1TRPM8SLC1A3SLC1A2 | |
| SCHEMBL9377438 | 0.76 | ALOX5 (0.43) | ALOX5RIPK1TRPM8 | |
| SCHEMBL9539758 | 0.76 | ALOX5 (0.58) | ALOX5 | |
| SCHEMBL9539825 | 0.75 | ALOX5 (0.39) | ALOX5RIPK1TRPM8 | |
| SCHEMBL9541385 | 0.75 | ALOX5 (0.59) | ALOX5ALDH1A1 | |
| SCHEMBL9373644 | 0.75 | ALOX5 (0.51) | ALOX5RIPK1TRPM8 | |
| SCHEMBL9539698 | 0.73 | SLC1A3 (0.57) | ALOX5ALDH1A1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL9584897 | 0.73 | ALOX5 (0.56) | ALOX5ALDH1A1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL9538808 | 0.73 | ALOX5 (0.56) | ALOX5TRPM8SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL9373722 | 0.73 | ALOX5 (0.60) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993003719-A1 | ARYLALKYLETHER AND ARYLALKYLTHIOETHER INHIBITORS OF LIPOXYGENASE ENZYME ACTIVITY | ABBOTT LABORATORIES (US) | 1993-03-04 | — | — | WO | disclosed |
| US-5183818-A | Also for inhibiting leukotriene biosynthesis | ABBOTT LABORATORIES (US) | 1993-02-02 | — | — | US | disclosed |