Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 14/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9539718 | 0.79 | ALOX5 (0.59) | ALOX5ALDH1A1MAPT | |
| SCHEMBL9584897 | 0.77 | ALOX5 (0.56) | ALOX5HPGDGAAALDH1A1MAPT | |
| SCHEMBL9539758 | 0.75 | ALOX5 (0.58) | ALOX5MAPT | |
| SCHEMBL9538808 | 0.75 | ALOX5 (0.56) | ALOX5 | |
| SCHEMBL9539835 | 0.75 | ALOX5 (0.43) | ALOX5ALDH1A1 | |
| SCHEMBL9539663 | 0.72 | SLC1A3 (0.57) | ALOX5ALDH1A1 | |
| SCHEMBL9539698 | 0.69 | SLC1A3 (0.57) | ALOX5ALDH1A1 | |
| SCHEMBL9539727 | 0.68 | ALOX5 (0.56) | ALOX5ALDH1A1MAPTTSHR | |
| SCHEMBL7334644 | 0.65 | ALOX5 (0.59) | ALOX5HPGDGAAALDH1A1MAPT | |
| SCHEMBL9584855 | 0.65 | ALOX5 (0.52) | ALOX5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993003719-A1 | ARYLALKYLETHER AND ARYLALKYLTHIOETHER INHIBITORS OF LIPOXYGENASE ENZYME ACTIVITY | ABBOTT LABORATORIES (US) | 1993-03-04 | — | — | WO | claimed |
| US-5183818-A | Also for inhibiting leukotriene biosynthesis | ABBOTT LABORATORIES (US) | 1993-02-02 | — | — | US | disclosed |