Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9060002 | 0.81 | SIGMAR1 (0.40) | HTR7MEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL9060356 | 0.70 | GRIN2D (0.44) | RAB9ASIGMAR1PLAUGRIN2DGRIN3B | |
| SCHEMBL9311522 | 0.69 | GRIN2D (0.46) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL30478007 | 0.68 | ALDH1A1 (0.58) | HTR7KMT2ASMN1; SMN2RAB9AKDM4E | |
| SCHEMBL7411224 | 0.68 | ALDH1A1 (0.58) | HTR7KMT2ASMN1; SMN2RAB9AKDM4E | |
| SCHEMBL3788477 | 0.68 | ALDH1A1 (0.46) | HTR7SMN1; SMN2RAB9AKDM4EALDH1A1 | |
| SCHEMBL29634405 | 0.68 | ALDH1A1 (0.46) | HTR7SMN1; SMN2RAB9AKDM4EALDH1A1 | |
| SCHEMBL8441436 | 0.68 | ALDH1A1 (0.50) | HTR7MEN1KMT2ASMN1; SMN2RAB9A | |
| Hydrochloric Acid SCHEMBL9535077 | 0.66 | ALDH1A1 (0.45) | HTR7SMN1; SMN2RAB9AKDM4EALDH1A1 | |
| SCHEMBL9539853 | 0.66 | HTR7 (0.38) | HTR7MEN1KMT2ASMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536151-A1 | ORTHOSUBSTITUTED BIPHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM. | BOOTS CO PLC (GB) | 1993-04-14 | — | — | EP | disclosed |