Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9540053 | 0.84 | ALDH1A1 (0.33) | HSD17B10ALDH1A1GAAMAPK1MAPT | |
| SCHEMBL12311137 | 0.72 | ALDH1A1 (0.52) | HSD17B10ALDH1A1GAAMAPK1MAPT | |
| SCHEMBL4626925 | 0.71 | TSHR (0.50) | HSD17B10ALDH1A1GAAMAPK1MAPT | |
| SCHEMBL10545243 | 0.71 | POLB (0.38) | HSD17B10ALDH1A1GAAMAPK1MAPT | |
| SCHEMBL11387602 | 0.71 | ALDH1A1 (0.45) | HSD17B10ALDH1A1GAAMAPK1MAPT | |
| SCHEMBL9540060 | 0.71 | TSHR (0.33) | HSD17B10L3MBTL1SMN1; SMN2TSHRPOLB | |
| SCHEMBL9543957 | 0.71 | ALDH1A1 (0.33) | HSD17B10ALDH1A1GAAMAPK1 | |
| SCHEMBL9541212 | 0.71 | ALDH1A1 (0.33) | HSD17B10ALDH1A1GAAMAPK1MAPT | |
| SCHEMBL15713806 | 0.70 | ALDH1A1 (0.54) | HSD17B10ALDH1A1GAAMAPK1MAPT | |
| SCHEMBL470885 | 0.68 | HSD17B1 (0.38) | HSD17B10ALDH1A1GAAMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993012795-A1 | QUINAZOLIN-4(3H)-ONE DERIVATIVES AS ANTICOCCIDIAL AGENTS | GLAZER EDWARD A (US) | 1993-07-08 | — | — | WO | disclosed |
| US-4920224-A | CHEMICAL INTERMEDIATES | PFIZER INC. (US) | 1990-04-24 | — | — | US | disclosed |
| US-4849518-A | ANTIPROTOZOA IN POULTRY | PFIZER INC. (US) | 1989-07-18 | — | — | US | disclosed |
| US-4762838-A | Quinazolin-4(3H)-one derivatives as anticoccidial agents | PFIZER INC. (US) | 1988-08-09 | — | — | US | disclosed |