Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.30 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.30 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.30 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9543957 | 0.80 | ALDH1A1 (0.33) | ALDH1A1HSD17B10GAAMAPK1 | |
| SCHEMBL9540053 | 0.80 | ALDH1A1 (0.33) | ALDH1A1HSD17B10MAPTKDM4ENPC1 | |
| SCHEMBL23813891 | 0.72 | ALDH1A1 (0.41) | ALDH1A1HSD17B10MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL9540066 | 0.71 | HSD17B10 (0.35) | ALDH1A1HSD17B10MAPTKDM4ENPC1 | |
| SCHEMBL11387602 | 0.70 | ALDH1A1 (0.45) | ALDH1A1HSD17B10MAPTKDM4ENPC1 | |
| SCHEMBL9541207 | 0.70 | SLC6A2 (0.31) | ALDH1A1HSD17B10MAPT | |
| SCHEMBL13517391 | 0.70 | UHRF1 (0.40) | ALDH1A1HSD17B10MAPTKDM4ENPC1 | |
| SCHEMBL5951820 | 0.69 | DGAT1 (0.40) | MAPTKDM4EHTT | |
| SCHEMBL24697160 | 0.69 | IKBKE (0.30) | MAPK1 | |
| SCHEMBL3530679 | 0.69 | KEAP1 (0.50) | ALDH1A1HSD17B10MAPTKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993012795-A1 | QUINAZOLIN-4(3H)-ONE DERIVATIVES AS ANTICOCCIDIAL AGENTS | GLAZER EDWARD A (US) | 1993-07-08 | — | — | WO | disclosed |
| US-4920224-A | CHEMICAL INTERMEDIATES | PFIZER INC. (US) | 1990-04-24 | — | — | US | disclosed |
| US-4849518-A | ANTIPROTOZOA IN POULTRY | PFIZER INC. (US) | 1989-07-18 | — | — | US | disclosed |
| US-4762838-A | Quinazolin-4(3H)-one derivatives as anticoccidial agents | PFIZER INC. (US) | 1988-08-09 | — | — | US | disclosed |