Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.45 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 3/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9186461 | 0.83 | TAAR1 (0.59) | TAAR1 | |
| SCHEMBL18531114 | 0.79 | KDM4E (0.46) | PPARGPPARATAAR1 | |
| SCHEMBL9082119 | 0.77 | PPARG (0.56) | PPARGPPARANPY5RLTA4HSRD5A2 | |
| SCHEMBL11028204 | 0.77 | TAAR1 (0.52) | TAAR1MEN1KMT2A | |
| SCHEMBL9252743 | 0.76 | LTA4H (0.55) | PPARGPPARANPY5RLTA4HSLC2A1 | |
| SCHEMBL7562938 | 0.74 | MMP12 (0.48) | NPY5RLTA4HSRD5A2MEN1KMT2A | |
| SCHEMBL7562523 | 0.74 | MMP12 (0.42) | SLC2A1 | |
| SCHEMBL7568124 | 0.74 | MMP12 (0.48) | NPY5RLTA4HSRD5A2MEN1KMT2A | |
| SCHEMBL6721099 | 0.74 | LTA4H (0.48) | LTA4HSRD5A2MEN1KMT2A | |
| SCHEMBL7560598 | 0.74 | LTA4H (0.52) | LTA4HSRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532693-A1 | 1,4-DIAMINO-2,3-DIHYDROXYBUTANES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1993-03-24 | — | — | EP | disclosed |