Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7562938 | 1.00 | MMP12 (0.48) | MMP12MMP13SRD5A2FFAR1MEN1 | |
| SCHEMBL7562523 | 0.85 | MMP12 (0.42) | MMP12MMP13FFAR1 | |
| SCHEMBL7564712 | 0.82 | TTR (0.48) | MEN1ALDH1A1KMT2ALMNAADRB2 | |
| SCHEMBL7570062 | 0.81 | MMP12 (0.45) | MMP12MMP13SRD5A2FFAR1MEN1 | |
| SCHEMBL9081379 | 0.81 | MMP12 (0.52) | MMP12MMP13SRD5A2FFAR1LTA4H | |
| SCHEMBL7563386 | 0.80 | NPSR1 (0.43) | FFAR1MEN1ALDH1A1KMT2ALMNA | |
| SCHEMBL7561384 | 0.77 | ALDH1A1 (0.43) | MMP12MMP13FFAR1MEN1ALDH1A1 | |
| SCHEMBL8294115 | 0.75 | FFAR1 (0.53) | MMP12MMP13SRD5A2FFAR1LTA4H | |
| SCHEMBL7562926 | 0.75 | FFAR1 (0.50) | MMP12MMP13SRD5A2FFAR1NPY5R | |
| SCHEMBL9540179 | 0.74 | PPARG (0.47) | SRD5A2MEN1KMT2ALTA4HNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882703-B1 | CYCLIC AMIC ACID DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2002-08-14 | — | — | EP | disclosed |
| US-6011174-A | INHIBIT PROTEIN-FARNESYL TRANSFERASE (PFT) IN VIVO THEREBY TO SUPPRESS FUNCTION OF ONCOGENE PROTEIN RAS AND THUS PRESENT ANTITUMOR ACTIVITIES, | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0882703-A1 | CYCLIC AMIC ACID DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-12-09 | — | — | EP | disclosed |