Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CNR1 | P21554 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Phenylphenol SCHEMBL9540236 | 0.81 | ESR2 (0.46) | MAPTESR2HSD17B1HSD17B2CYP3A4 | |
| 2-Phenylphenol SCHEMBL574631 | 0.77 | HPGD (0.57) | MAPTTHRBESR2HSD17B1HSD17B2 | |
| Orthocresol SCHEMBL574630 | 0.77 | ESR2 (0.51) | MAPTTHRBESR2HSD17B1HSD17B2 | |
| SCHEMBL29383789 | 0.75 | BACE1 (0.62) | MAPTESR2CYP1A2HSD17B1HSD17B2 | |
| SCHEMBL329155 | 0.75 | BACE1 (0.62) | MAPTESR2CYP1A2HSD17B1HSD17B2 | |
| Phosphine SCHEMBL27555075 | 0.73 | BACE1 (0.60) | MAPTESR2HSD17B1HSD17B2CYP3A4 | |
| Methane SCHEMBL27581120 | 0.73 | BACE1 (0.60) | MAPTESR2HSD17B1HSD17B2CYP3A4 | |
| SCHEMBL28097322 | 0.70 | BACE1 (0.56) | MAPTTHRBESR2HSD17B1HSD17B2 | |
| Metacresol SCHEMBL8655417 | 0.70 | ACHE (0.71) | ESR2CYP2C19CYP1A2ACHECYP3A4 | |
| Chloroxylenol SCHEMBL4724878 | 0.70 | CYP3A4 (0.73) | ESR2CYP2C19CYP1A2HSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993002658-A1 | ORAL COMPOSITIONS EFFECTIVE AGAINST PLAQUE AND GINGIVITIS | THE PROCTER & GAMBLE COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |