Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 4/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Phenylphenol SCHEMBL574631 | 0.85 | HPGD (0.57) | ESR2ALOX5HPGDALDH1A1BCL2L1 | |
| Chlorocresol SCHEMBL9709045 | 0.81 | ESR2 (0.47) | ESR2HPGDALDH1A1HSD17B10ALOX15 | |
| Chloroxylenol SCHEMBL9540232 | 0.81 | MAPT (0.46) | ESR2HPGDALDH1A1ALOX15CYP3A4 | |
| Chlorocresol SCHEMBL27317750 | 0.78 | ESR2 (0.45) | ESR2HPGDALDH1A1HSD17B10ALOX15 | |
| Orthocresol SCHEMBL574630 | 0.74 | ESR2 (0.51) | ESR2HPGDALDH1A1BCL2L1HSD17B10 | |
| Chlorocresol SCHEMBL2368412 | 0.73 | HSD17B10 (0.48) | ESR2HPGDALDH1A1HSD17B10ALOX15 | |
| Chloroxylenol SCHEMBL5569330 | 0.73 | CYP3A4 (0.73) | ESR2HPGDHSD17B10ALOX15CYP3A4 | |
| Phenol SCHEMBL28106636 | 0.72 | TSHR (0.45) | ESR2HPGDALDH1A1HSD17B10ALOX15 | |
| Biphenyl SCHEMBL5712287 | 0.72 | HSD17B1 (0.66) | ESR2ALOX5HPGDALDH1A1BCL2L1 | |
| Chlorocresol SCHEMBL8736464 | 0.70 | ESR2 (0.52) | ESR2ALDH1A1BCL2L1HSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993002658-A1 | ORAL COMPOSITIONS EFFECTIVE AGAINST PLAQUE AND GINGIVITIS | THE PROCTER & GAMBLE COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |