Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2061229 | 0.85 | MAPT (0.37) | MAPTALDH1A1KMT2AMEN1CYP3A4 | |
| SCHEMBL2060734 | 0.84 | MAPT (0.33) | MAPTALDH1A1KMT2AMEN1CYP3A4 | |
| SCHEMBL5010661 | 0.73 | GAA (0.41) | MAPTALDH1A1KMT2AMEN1CYP3A4 | |
| SCHEMBL10393520 | 0.71 | MAPT (0.50) | MAPTALDH1A1KMT2AMEN1CYP2D6 | |
| SCHEMBL2255760 | 0.71 | ALDH1A1 (0.44) | MAPTALDH1A1KMT2AMEN1CYP3A4 | |
| SCHEMBL10393521 | 0.71 | MAPT (0.50) | MAPTALDH1A1KMT2AMEN1CYP2D6 | |
| SCHEMBL1169394 | 0.71 | MAPT (0.52) | MAPTALDH1A1KMT2AMEN1CYP3A4 | |
| SCHEMBL10556520 | 0.71 | PKM (0.44) | MAPTALDH1A1KMT2AMEN1CYP3A4 | |
| SCHEMBL2417773 | 0.71 | MAPT (0.45) | MAPTALDH1A1KMT2AMEN1CYP3A4 | |
| SCHEMBL9540234 | 0.71 | GLB1 (0.39) | MAPTALDH1A1KMT2AMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993003725-A1 | 5-HT4 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1993-03-04 | — | — | WO | disclosed |