Quizalofop

Quizalofop

SCHEMBL9540398

CC(Oc1ccc(Oc2cnc3cc(Cl)ccc3n2)cc1)C(=O)O.CCOC(=O)S

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.61
ALDH1A1 P00352 3/20 0.61
MAPT P10636 3/20 0.61
CYP3A4 P08684 2/20 0.61
LMNA P02545 2/20 0.61
SMN1; SMN2 Q16637 2/20 0.61
HPGD P15428 2/20 0.61
TP53 P04637 1/20 0.61
ALOX15 P16050 1/20 0.61
NFKB1 P19838 1/20 0.61
HIF1A Q16665 1/20 0.61
GMNN O75496 1/20 0.61
APEX1 P27695 1/20 0.61
PMP22 Q01453 1/20 0.61
NPSR1 Q6W5P4 1/20 0.61
HTT P42858 4/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
MAP4K4 O95819 2/20 0.41
TSHR P16473 1/20 0.38
HTR2A P28223 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quizalofop Ethyl Ester SCHEMBL8537282 0.92 CYP1A2 (0.63) CYP1A2ALDH1A1MAPTCYP3A4LMNA
Quizalofop SCHEMBL63325 0.90 ALDH1A1 (0.72) CYP1A2ALDH1A1MAPTCYP3A4LMNA
Quizalofop SCHEMBL111413 0.90 ALDH1A1 (0.72) CYP1A2ALDH1A1MAPTCYP3A4LMNA
Quizalofop SCHEMBL19210826 0.90 ALDH1A1 (0.72) CYP1A2ALDH1A1MAPTCYP3A4LMNA
Quizalofop SCHEMBL1010164 0.90 ALDH1A1 (0.72) CYP1A2ALDH1A1MAPTCYP3A4LMNA
Quizalofop SCHEMBL29763487 0.90 ALDH1A1 (0.72) CYP1A2ALDH1A1MAPTCYP3A4LMNA
Quizalofop SCHEMBL10942454 0.89 ALDH1A1 (0.71) CYP1A2ALDH1A1MAPTCYP3A4LMNA
Quizalofop-P-Ethyl SCHEMBL29474422 0.88 MAPT (0.67) CYP1A2ALDH1A1MAPTCYP3A4LMNA
Quizalofop Ethyl Ester SCHEMBL9139248 0.88 MAPT (0.67) CYP1A2ALDH1A1MAPTCYP3A4LMNA
Quizalofop-P-Ethyl SCHEMBL53466 0.88 MAPT (0.67) CYP1A2ALDH1A1MAPTCYP3A4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993003020-A1 HERBICIDAL QUINOXALINYLOXY ETHERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-02-18 WO disclosed