Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 3/20 | 0.32 |
| ▸ | CDK2 | P24941 | 3/20 | 0.32 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.32 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.32 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.31 |
| ▸ | MMP9 | P14780 | 2/20 | 0.31 |
| ▸ | MMP12 | P39900 | 2/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.30 |
| ▸ | CLK1 | P49759 | 1/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.30 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9543043 | 0.93 | ALDH1A1 (0.38) | ALDH1A1HPGDHSD17B10CDK1CDK2 | |
| SCHEMBL9540186 | 0.64 | LMNA (0.46) | ALDH1A1HPGDCDK1CDK2CCNB1 | |
| SCHEMBL28445719 | 0.62 | STS (0.43) | ALDH1A1HSD17B10CYP19A1EPHX1MMP9 | |
| SCHEMBL31643443 | 0.61 | MMP9 (0.41) | ALDH1A1CYP19A1EPHX1MMP9MMP12 | |
| SCHEMBL11589654 | 0.61 | EPHX1 (0.60) | ALDH1A1EPHX1SMN1; SMN2 | |
| SCHEMBL13387598 | 0.61 | EPHX1 (0.60) | ALDH1A1EPHX1SMN1; SMN2 | |
| SCHEMBL8426647 | 0.61 | EPHX1 (0.60) | ALDH1A1EPHX1SMN1; SMN2 | |
| SCHEMBL8991654 | 0.61 | EPHX1 (0.60) | ALDH1A1EPHX1SMN1; SMN2 | |
| SCHEMBL984315 | 0.61 | EPHX1 (0.60) | ALDH1A1EPHX1SMN1; SMN2 | |
| SCHEMBL37472 | 0.61 | EPHX1 (0.60) | ALDH1A1EPHX1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993003033-A1 | CARBONATE-SUBSTITUTED IMIDAZO[4,5-d] PYRIDAZINE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G. D. SEARLE & CO. (US) | 1993-02-18 | — | — | WO | claimed |