SCHEMBL9540852

SCHEMBL9540852

CCOC(=O)CC(=O)C1C2C=CC(C2=C(C)C)C1C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 1/20 0.46
ALDH1A1 P00352 7/20 0.45
TSHR P16473 2/20 0.45
MGAM O43451 1/20 0.39
GAA P10253 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
PPM1B O75688 2/20 0.36
RAB9A P51151 1/20 0.36
KDM4E B2RXH2 1/20 0.36
POLB P06746 2/20 0.34
MAPT P10636 1/20 0.34
KMT2A Q03164 1/20 0.33
CASP6 P55212 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7813673 0.78 FPR2 (0.60) FPR2ALDH1A1TSHRGAAPOLB
SCHEMBL9542336 0.74 MGAM (0.45) ALDH1A1TSHRMGAMGAASI
SCHEMBL9540948 0.72 ALDH1A1 (0.52) ALDH1A1MGAMGAASIMGAM2
Malonic Acid Diethyl Ester SCHEMBL29008218 0.64 GAA (0.83) ALDH1A1TSHRMGAMGAASI
Malonic Acid Diethyl Ester SCHEMBL27258261 0.62 GAA (0.79) ALDH1A1TSHRMGAMGAASI
SCHEMBL24695622 0.62 MGAM (0.50) ALDH1A1TSHRMGAMGAASI
Malonic Acid Diethyl Ester SCHEMBL27943809 0.61 GAA (0.88) ALDH1A1TSHRMGAMGAASI
Malonic Acid Diethyl Ester SCHEMBL9439825 0.61 GAA (0.88) ALDH1A1TSHRMGAMGAASI
Malonic Acid Diethyl Ester SCHEMBL28126343 0.61 GAA (0.88) ALDH1A1TSHRMGAMGAASI
Benzene SCHEMBL28270557 0.61 GAA (0.61) ALDH1A1TSHRMGAMGAASI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993014062-A1 ANTHELMINTIC β-KETOAMIDES THE UPJOHN COMPANY (US) 1993-07-22 WO claimed
WO-1993014062-A1 ANTHELMINTIC β-KETOAMIDES THE UPJOHN COMPANY (US) 1993-07-22 WO disclosed