Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 6/20 | 0.58 |
| ▸ | AR | P10275 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | ESR1 | P03372 | 2/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | SHBG | P04278 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.54 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.54 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12434544 | 0.84 | PGR (0.74) | PGRARLMNAESR1SLC6A4 | |
| SCHEMBL9542447 | 0.83 | PDK1 (0.59) | PGRARLMNAESR1SLC6A4 | |
| SCHEMBL8426985 | 0.83 | PGR (0.54) | PGRARLMNAESR1SLC6A4 | |
| SCHEMBL9007368 | 0.82 | PGR (0.56) | PGRARLMNAESR1SLC6A4 | |
| SCHEMBL9007371 | 0.82 | PGR (0.56) | PGRARLMNAESR1SLC6A4 | |
| SCHEMBL8423652 | 0.82 | PGR (0.53) | PGRARLMNAESR1SLC6A4 | |
| SCHEMBL9541966 | 0.79 | PDK1 (0.43) | PGRARLMNAESR1SLC6A4 | |
| SCHEMBL8678004 | 0.78 | PGR (0.76) | PGRARLMNAESR1SLC6A4 | |
| Normethandrone SCHEMBL23801610 | 0.78 | PGR (0.73) | PGRARLMNAESR1SLC6A4 | |
| Normethandrone SCHEMBL148631 | 0.78 | PGR (0.73) | PGRARLMNAESR1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013122-A1 | 3-METHYLSULPHONYLHYDRAZONO AND 3-OXYIMINO STEROIDS, A METHOD OF PREPARING THEM, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND THEIR USE IN THE PREPARATION OF DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-07-08 | — | — | WO | disclosed |