Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 4/20 | 0.37 |
| ▸ | DRD3 | P35462 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9541303 | 0.71 | ADRA2A (0.43) | ADRA2AADRA2BADRA2CCYP2D6ADRA1D | |
| SCHEMBL3886570 | 0.67 | DRD2 (0.42) | CYP2D6DRD2DRD3HTR1A | |
| SCHEMBL26027881 | 0.66 | ADRA2A (0.58) | ADRA2AADRA2BADRA2CCYP2D6ADRA1D | |
| SCHEMBL8083358 | 0.66 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CCYP2D6ADRA1D | |
| Hydrochloric Acid SCHEMBL10871080 | 0.64 | NPSR1 (1.00) | ADRA2AADRA2BADRA2CCYP2D6ADRA1D | |
| SCHEMBL10882588 | 0.64 | ADRA2A (0.69) | ADRA2AADRA2BADRA2CCYP2D6ADRA1D | |
| SCHEMBL14945587 | 0.63 | ADRA2A (0.79) | ADRA2AADRA2BADRA2CCYP2D6ADRA1D | |
| SCHEMBL6370118 | 0.63 | ADRA2A (0.57) | ADRA2AADRA2BADRA2CCYP2D6ADRA1D | |
| SCHEMBL28906340 | 0.62 | ADRA2A (0.53) | ADRA2AADRA2BADRA2CCYP2D6ADRA1D | |
| SCHEMBL16233584 | 0.61 | ADRA2A (0.50) | ADRA2AADRA2BADRA2CCYP2D6ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993004686-A1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-03-18 | — | — | WO | disclosed |