Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PNLIP | P16233 | 6/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10580567 | 0.79 | ALDH1A1 (0.68) | ALDH1A1HPGDPOLBGAAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL10667156 | 0.78 | ALDH1A1 (0.67) | ALDH1A1HPGDPOLBGAAL3MBTL1 | |
| SCHEMBL9543906 | 0.77 | MEN1 (0.56) | ALDH1A1HPGDPOLBGAAL3MBTL1 | |
| SCHEMBL8901023 | 0.77 | PNLIP (0.52) | ALDH1A1HPGDPOLBGAAL3MBTL1 | |
| SCHEMBL11577659 | 0.76 | GAA (0.54) | ALDH1A1HPGDPOLBGAAL3MBTL1 | |
| SCHEMBL7023175 | 0.76 | GAA (0.58) | ALDH1A1HPGDPOLBGAAL3MBTL1 | |
| SCHEMBL17351273 | 0.74 | MAPT (0.54) | ALDH1A1HPGDL3MBTL1CYP1A2CYP2C9 | |
| SCHEMBL28521601 | 0.72 | TSHR (0.63) | ALDH1A1POLBSMN1; SMN2MAPTSTK39 | |
| SCHEMBL2778881 | 0.72 | MAPT (0.61) | ALDH1A1HPGDGAAL3MBTL1CYP1A2 | |
| SCHEMBL29842430 | 0.72 | MAPT (0.61) | ALDH1A1HPGDGAAL3MBTL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993012795-A1 | QUINAZOLIN-4(3H)-ONE DERIVATIVES AS ANTICOCCIDIAL AGENTS | GLAZER EDWARD A (US) | 1993-07-08 | — | — | WO | disclosed |
| US-4920224-A | CHEMICAL INTERMEDIATES | PFIZER INC. (US) | 1990-04-24 | — | — | US | disclosed |
| US-4849518-A | ANTIPROTOZOA IN POULTRY | PFIZER INC. (US) | 1989-07-18 | — | — | US | disclosed |
| US-4762838-A | Quinazolin-4(3H)-one derivatives as anticoccidial agents | PFIZER INC. (US) | 1988-08-09 | — | — | US | disclosed |