Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNLIP | P16233 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4759903 | 0.90 | ALDH1A1 (0.52) | PNLIPMAPTALDH1A1POLBKDM4E | |
| SCHEMBL30024982 | 0.90 | ALDH1A1 (0.52) | PNLIPMAPTALDH1A1POLBKDM4E | |
| SCHEMBL11577659 | 0.87 | GAA (0.54) | PNLIPMAPTALDH1A1POLBKDM4E | |
| SCHEMBL2748501 | 0.85 | CTNNB1 (0.54) | MAPTALDH1A1POLBKDM4EMEN1 | |
| SCHEMBL9097722 | 0.84 | PNLIP (0.52) | PNLIPMAPTALDH1A1POLBKDM4E | |
| SCHEMBL711924 | 0.83 | KDM4E (0.59) | MAPTALDH1A1POLBKDM4EMEN1 | |
| SCHEMBL8902333 | 0.82 | PARP10 (0.50) | PNLIPMAPTALDH1A1POLBKDM4E | |
| SCHEMBL20945312 | 0.81 | KDM4E (0.65) | MAPTALDH1A1POLBKDM4EMEN1 | |
| SCHEMBL22891351 | 0.79 | CYP1A2 (0.57) | ALDH1A1POLBKDM4EHPGDCYP2C9 | |
| SCHEMBL4448975 | 0.78 | PTGER4 (0.62) | ALDH1A1POLBKDM4EHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1043349-C | New sulfuric acid esters of sugar alcohols | HOFFMANN LA ROCHE (CH) | 1999-05-12 | — | — | CN | disclosed |
| EP-0663391-B1 | Sulphuric acid esters of sugar alcohols for the treatment of arteriosclerotic changes in the vascular walls | HOFFMANN LA ROCHE (CH) | 1997-04-09 | — | — | EP | disclosed |
| US-5521160-A | COMPOUNDS FOR TREATMENT OF ATHERIOSCLEROSIS IN BLOOD VESSELS AND PREVENTION OF RESTENOSIS AFTER ANGIOPLASTY | HOFFMANN-LA ROCHE INC. (US) | 1996-05-28 | — | — | US | disclosed |
| CN-1109889-A | New sulfuric acid esters of sugar alcohols | HOFFMANN LA ROCHE (CH) | 1995-10-11 | — | — | CN | disclosed |
| EP-0663391-A1 | Sulphuric acid esters of sugar alcohols for the treatment of arteriosclerotic changes in the vascular walls | F. HOFFMANN-LA ROCHE AG (CH) | 1995-07-19 | — | — | EP | disclosed |