Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.51 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | UGCG | Q16739 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14341090 | 0.88 | CYP1A2 (0.47) | ALDH1A1SMN1; SMN2HPGDADORA2ASCN9A | |
| SCHEMBL28431110 | 0.85 | SCN9A (0.48) | ALDH1A1SMN1; SMN2HPGDSCN9AKDM4E | |
| SCHEMBL29137491 | 0.84 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2HPGDADORA2ASCN9A | |
| SCHEMBL9097189 | 0.81 | PDE5A (0.49) | ALDH1A1HPGDSCN9AKDM4ELMNA | |
| SCHEMBL7642915 | 0.79 | MAPT (0.66) | ALDH1A1SMN1; SMN2HPGDSCN9AKDM4E | |
| SCHEMBL158912 | 0.78 | BCHE (0.58) | ALDH1A1SMN1; SMN2HPGDKDM4EGAA | |
| SCHEMBL29986041 | 0.78 | BCHE (0.58) | ALDH1A1SMN1; SMN2HPGDKDM4EGAA | |
| SCHEMBL7004339 | 0.78 | MAOA (0.46) | ALDH1A1SMN1; SMN2HPGDSCN9AKDM4E | |
| SCHEMBL3648742 | 0.77 | CYP2A6 (0.55) | ALDH1A1SMN1; SMN2HPGDADORA2ASCN9A | |
| SCHEMBL7445924 | 0.77 | CYP2A6 (0.40) | ALDH1A1SMN1; SMN2HPGDSCN9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1868998-B1 | NEW HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS, IN PARTICULAR AS ANTI-ALZHEIMER AGENTS | VFP THERAPIES (FR) | 2016-05-25 | — | — | EP | disclosed |
| CN-103476781-A | Novel tetradentate platinum complexes | UNIVERSAL DISPLAY CORP | 2013-12-25 | — | — | CN | disclosed |
| CN-101631793-B | Electroluminescent metal complexes of benzotriazoles | BASF SE | 2013-12-25 | — | — | CN | disclosed |
| US-7977354-B2 | Heterocyclic compounds, their preparation and their use as medicaments, in particular as anti-alzheimer agents | INSA ROUEN (FR) | 2011-07-12 | — | — | US | disclosed |
| WO-2011006353-A1 | LUMINESCENT GOLD(III) COMPOUNDS CONTAINING BIDENTATE LIGAND FOR ORGANIC LIGHT-EMITTING DEVICES AND THEIR PREPARATION | THE UNIVERSITY OF HONG KONG (CN) | 2011-01-20 | — | — | WO | disclosed |
| CN-101631793-A | Electroluminescent metal complexes of benzotriazoles | BASF SE | 2010-01-20 | — | — | CN | disclosed |
| US-20090062279-A1 | HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS, IN PARTICULAR AS ANTI-ALZHEIMER AGENTS | INSA ROUEN (FR) | 2009-03-05 | — | — | US | disclosed |
| US-20090039776-A1 | ORGANOMETALLIC COMPLEX AND ORGANIC LIGHT-EMITTING ELEMENT USING SAME | CANON KABUSHIKI KAISHA (JP) | 2009-02-12 | — | — | US | disclosed |
| CN-100375749-C | Luminescence device and display apparatus | CANON KK (JP) | 2008-03-19 | — | — | CN | disclosed |
| EP-1868998-A2 | NEW HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS, IN PARTICULAR AS ANTI-ALZHEIMER AGENTS | Insa Rouen (FR) | 2007-12-26 | — | — | EP | disclosed |
| EP-1731507-A1 | New heterocyclic compounds, their preparation and their use as medicaments, in particular as anti-alzheimer agents | Institut National des Sciences Appliquees de Rouen (INSA) (FR) | 2006-12-13 | — | — | EP | disclosed |
| CN-1285601-C | Light emitting device and display | CANON KK (JP) | 2006-11-22 | — | — | CN | disclosed |
| WO-2006103120-A2 | NEW HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS, IN PARTICULAR AS ANTI-ALZHEIMER AGENTS | INSA ROUEN (FR) | 2006-10-05 | — | — | WO | disclosed |
| CN-1781925-A | Luminescence device and display apparatus | CANON KK (JP) | 2006-06-07 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062279-A1 | HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS, IN PARTICULAR AS ANTI-ALZHEIMER AGENTS | NLN, SNCA, APP | ALDH1A1 1663/4885SMN1; SMN2 403/4885HPGD 93/4885 |
| US-20090039776-A1 | ORGANOMETALLIC COMPLEX AND ORGANIC LIGHT-EMITTING ELEMENT USING SAME | LAGE3, ORC3, INTS9 | ALDH1A1 251/4885SMN1; SMN2 1885/4885HPGD 3565/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.