Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.33 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.33 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18502845 | 1.00 | EPHX1 (0.37) | EPHX1HTR2AHRH1KISS1RPRMT3 | |
| SCHEMBL21283080 | 1.00 | EPHX1 (0.37) | EPHX1HTR2AHRH1KISS1RPRMT3 | |
| SCHEMBL9541590 | 0.86 | PRMT3 (0.36) | HTR2AHRH1PRMT3CARM1PRMT6 | |
| SCHEMBL18806384 | 0.80 | — | — | |
| SCHEMBL16752057 | 0.78 | KISS1R (0.35) | EPHX1HTR2AHRH1KISS1RPRMT3 | |
| SCHEMBL16752077 | 0.78 | HTR2A (0.34) | EPHX1HTR2AHRH1KISS1RPRMT3 | |
| SCHEMBL20107217 | 0.77 | — | — | |
| SCHEMBL20368642 | 0.75 | ALDH1A1 (0.39) | — | |
| SCHEMBL5948812 | 0.75 | ALDH1A1 (0.39) | — | |
| SCHEMBL5948733 | 0.73 | OPRM1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402329-B1 | Analgetic phenylsulphonamides | BOEHRINGER INGELHEIM INT (DE) | 2013-05-22 | — | — | EP | disclosed |