Edetol

Edetol

SCHEMBL9541672

C=C(C)C(=O)O.C=C(C)C(=O)O.CC(O)CN(CCN(CC(C)O)CC(C)O)CC(C)O

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.33
TSHR P16473 2/20 0.32
KMT2A Q03164 1/20 0.32
ATM Q13315 1/20 0.32
TDP1 Q9NUW8 2/20 0.31
EYA2 O00167 1/20 0.31
APP P05067 1/20 0.31
ACE P12821 1/20 0.31
TET2 Q6N021 3/20 0.30
TET3 O43151 1/20 0.30
TET1 Q8NFU7 1/20 0.30
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA9 Q16790 1/20 0.30
LMNA P02545 1/20 0.30
CHRM2 P08172 1/20 0.30
ADRA2A P08913 1/20 0.30
ALOX15 P16050 1/20 0.30
DRD1 P21728 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Edetol SCHEMBL9541642 1.00 KDM4E (0.33) KDM4ETSHRKMT2AATMTDP1
Edetol SCHEMBL10496053 0.80 KDM4E (0.35) KDM4EKMT2AATM
Methacrylic Acid SCHEMBL6673027 0.79 HPGD (0.33) KDM4ETSHRKMT2ATET2TET3
Edetol SCHEMBL48412 0.79 TSHR (0.39) KDM4ETSHRKMT2AATMTDP1
Edetol SCHEMBL2803498 0.79 TSHR (0.39) KDM4ETSHRKMT2AATMTDP1
Acetic Acid SCHEMBL22788463 0.77 KDM4E (0.39) KDM4ETSHRKMT2AATMTDP1
Acetic Acid SCHEMBL7780427 0.77 KDM4E (0.39) KDM4ETSHRKMT2AATMTDP1
Edetol SCHEMBL5596270 0.77 TDP1 (0.61) KDM4ETSHRKMT2AATMTDP1
SCHEMBL2619263 0.77 KMT2A (0.36) KDM4ETSHRKMT2AATMTDP1
SCHEMBL9785645 0.77 KDM4E (0.38) KDM4ETSHRKMT2AATMTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0263605-B1 WOUND DRESSING EDISON POLYMER INNOVATION CORPORATION ( EPIC) (US) 1992-05-06 EP claimed
US-4889530-A Wound dressing containing acrylate or methacrylate hydrogel polymer UNIVERSITY OF AKRON (US) 1989-12-26 US claimed
US-4781921-A Hydrogels of quadrol methacrylate polymers THE UNIVERSITY OF AKRON (US) 1988-11-01 US claimed
EP-0263605-A2 Wound dressing EDISON POLYMER INNOVATION CORPORATION ( EPIC) (US) 1988-04-13 EP claimed
WO-1993015122-A1 MEDICAL GRADE ADHESIVES AND THEIR PREPARATION THE UNIVERSITY OF AKRON (US) 1993-08-05 WO disclosed
US-5175246-A Reacting aliphatic diamines with diepoxide UNIVERSITY OF AKRON, THE (US) 1992-12-29 US disclosed
EP-0263605-B1 WOUND DRESSING EDISON POLYMER INNOVATION CORPORATION ( EPIC) (US) 1992-05-06 EP disclosed
US-4889530-A Wound dressing containing acrylate or methacrylate hydrogel polymer UNIVERSITY OF AKRON (US) 1989-12-26 US disclosed
US-4781921-A Hydrogels of quadrol methacrylate polymers THE UNIVERSITY OF AKRON (US) 1988-11-01 US disclosed
EP-0263605-A2 Wound dressing EDISON POLYMER INNOVATION CORPORATION ( EPIC) (US) 1988-04-13 EP disclosed