Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9541721 | 1.00 | DHFR (0.41) | DHFRPIK3CG | |
| SCHEMBL9541716 | 0.81 | DHFR (0.43) | DHFR | |
| SCHEMBL9543422 | 0.81 | DHFR (0.43) | DHFR | |
| SCHEMBL25167945 | 0.72 | PIM1 (0.48) | DHFRPIK3CG | |
| SCHEMBL25167944 | 0.72 | PIM1 (0.48) | DHFRPIK3CG | |
| SCHEMBL10965627 | 0.69 | ALDH1A1 (0.50) | DHFRPIK3CG | |
| SCHEMBL10965616 | 0.69 | ALDH1A1 (0.50) | DHFRPIK3CG | |
| SCHEMBL20228927 | 0.65 | DHFR (0.54) | DHFR | |
| SCHEMBL8403892 | 0.65 | DHFR (0.45) | DHFR | |
| SCHEMBL480956 | 0.65 | PIK3CG (0.42) | DHFRPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013102-A1 | DEAZAAMINOPTERINS | SOUTHERN RESEARCH INSTITUTE (US) | 1993-07-08 | — | — | WO | disclosed |