Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 2/20 | 0.40 |
| ▸ | RARG | P13631 | 2/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.33 |
| ▸ | GLRB | P48167 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9543676 | 0.86 | MAPT (0.38) | HDAC6HDAC1LMNAMAPK1RAB9A | |
| SCHEMBL499248 | 0.81 | CYP1A2 (0.39) | LMNAMAPK1EGFRALDH1A1 | |
| SCHEMBL9541842 | 0.81 | HCAR1 (0.44) | HDAC6HDAC1RAB9AHDAC3HDAC4 | |
| SCHEMBL9542523 | 0.80 | SLC6A3 (0.45) | HDAC6HDAC1HTTRAB9AEGFR | |
| SCHEMBL29781353 | 0.79 | CHRNA1 (0.49) | HDAC6HDAC1RAB9AALDH1A1CHRNA1 | |
| SCHEMBL9541142 | 0.76 | SCN9A (0.35) | HDAC6HDAC1LMNARAB9AHDAC3 | |
| SCHEMBL29055361 | 0.75 | HDAC6 (0.46) | RARARARGRARBHDAC6HDAC1 | |
| SCHEMBL21956939 | 0.75 | LMNA (0.39) | RARARARGRARBEPHX2NR1H4 | |
| SCHEMBL6119612 | 0.74 | SRD5A2 (0.48) | RARGRARBEPHX2NR1H4ALDH1A1 | |
| SCHEMBL14060389 | 0.72 | KDM4E (0.53) | LMNAMAPK1HTTRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993014063-A1 | FUNGICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-07-22 | — | — | WO | disclosed |