(Phenylsulfonyl)Benzene

(Phenylsulfonyl)Benzene

SCHEMBL9541906

NCc1ccccc1S(=O)(=O)c1ccccc1.O=S(=O)(c1ccccc1)c1ccccc1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 8/20 0.55
MMP2 P08253 5/20 0.50
MMP12 P39900 5/20 0.50
MMP13 P45452 5/20 0.50
MMP14 P50281 5/20 0.50
MMP9 P14780 4/20 0.50
MMP8 P22894 4/20 0.50
MMP16 P51512 4/20 0.50
MMP1 P03956 3/20 0.50
MMP3 P08254 3/20 0.50
LOX P28300 2/20 0.50
LOXL2 Q9Y4K0 2/20 0.50
MAOA P21397 1/20 0.50
SLC6A2 P23975 1/20 0.47
KMT2A Q03164 1/20 0.44
PTGDR2 Q9Y5Y4 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4613268 0.98 HTR6 (0.57) HTR6MMP2MMP12MMP13MMP14
Hydrochloric Acid SCHEMBL1019802 0.96 HTR6 (0.55) HTR6MMP2MMP12MMP13MMP14
SCHEMBL6680426 0.86 GAA (0.50) HTR6MMP2MMP12MMP13MMP14
SCHEMBL8761231 0.82 HTR6 (0.55) HTR6MMP2MMP12MMP13MMP14
SCHEMBL10181290 0.80 HSD11B1 (0.59) HTR6MMP2MMP12MMP13MMP14
SCHEMBL710752 0.78 CYP2D6 (0.62) HTR6MMP2MMP12MMP13MMP14
SCHEMBL8511247 0.78 HTR6 (0.52) HTR6MMP2MMP12MMP13MMP14
SCHEMBL708309 0.78 HTR6 (0.52) HTR6MMP2MMP12MMP13MMP14
SCHEMBL15363210 0.78 KIF18A (0.54) HTR6LOXLOXL2MAOA
Hydrochloric Acid SCHEMBL16527832 0.76 KIF18A (0.52) HTR6LOXLOXL2MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993002118-A1 A PROCESS FOR PREPARING ALKALI METAL SALTS OF POLYACRYLIC ACID BASED ON POLYSACCHARIDE TAECHANG MOOLSAN CO., LTD. (KR) 1993-02-04 WO disclosed