Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 9/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20149732 | 0.84 | RAB9A (0.61) | RAB9AALOX5APTBXA2RHTR3AHRH1 | |
| SCHEMBL23430131 | 0.77 | ALDH1A1 (0.59) | LMNAMAPTTP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL26350322 | 0.72 | LMNA (0.63) | RAB9ALMNAMAPTTP53SMN1; SMN2 | |
| SCHEMBL9542071 | 0.72 | ALOX5AP (0.57) | RAB9AALOX5APTBXA2RHTR3AHRH1 | |
| SCHEMBL7756931 | 0.70 | TNF (0.64) | LMNAMAPTTP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL3718063 | 0.70 | RAB9A (0.67) | RAB9AALOX5APTBXA2RHTR3AHRH1 | |
| SCHEMBL7761087 | 0.70 | GALR3 (0.67) | RAB9ATBXA2RHRH1CYP2D6KCNH2 | |
| SCHEMBL7761652 | 0.70 | TP53 (0.63) | RAB9AALOX5APHTR3AHRH1CYP2D6 | |
| SCHEMBL20866499 | 0.70 | CYP2C19 (0.56) | LMNATP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL9537915 | 0.69 | RAB9A (0.65) | RAB9AALOX5APTBXA2RHTR3AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993014083-A1 | PHARMACEUTICALLY ACTIVE SUBSTITUTED BENZIMIDAZOLE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-07-22 | — | — | WO | disclosed |