Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 3/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3678439 | 0.95 | MMP2 (0.47) | HTR2AHRH1MAOAEPHX1MMP2 | |
| SCHEMBL19812642 | 0.89 | EPHX1 (0.44) | HTR2AHRH1MAOAEPHX1MMP2 | |
| SCHEMBL7279393 | 0.84 | ACE (0.45) | EPHX1SLC6A3SIGMAR1ACESMN1; SMN2 | |
| SCHEMBL3366397 | 0.82 | TSHR (0.52) | EPHX1TAAR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL19812667 | 0.81 | EPHX1 (0.47) | MAOAEPHX1TAAR1MEN1KMT2A | |
| SCHEMBL1827653 | 0.81 | CSNK1E (0.50) | MMP2TAAR1MEN1KMT2ASIGMAR1 | |
| SCHEMBL7266299 | 0.80 | EPHX1 (0.54) | MAOAEPHX1TAAR1MEN1KMT2A | |
| SCHEMBL7266830 | 0.79 | ACE (0.51) | EPHX1TAAR1MEN1KMT2ASLC6A2 | |
| SCHEMBL12249323 | 0.79 | ACE (0.51) | EPHX1TAAR1MEN1KMT2ASLC6A2 | |
| SCHEMBL25457813 | 0.79 | CSNK1E (0.53) | MMP2PKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993000359-A1 | MODIFIED PEPTIDES TRANSPORTABLE INTO THE CENTRAL NERVOUS SYSTEM | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1993-01-07 | — | — | WO | claimed |
| WO-1993000359-A1 | MODIFIED PEPTIDES TRANSPORTABLE INTO THE CENTRAL NERVOUS SYSTEM | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1993-01-07 | — | — | WO | disclosed |