Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | FUT7 | Q11130 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | SELL | P14151 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SELP | P16109 | 1/20 | 0.36 |
| ▸ | FUT4 | P22083 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15112867 | 0.79 | KMT2A (0.44) | SERPINE1KMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL15851092 | 0.79 | ESRRG (0.46) | TDP1CA12CA1CA2TP53 | |
| SCHEMBL16675108 | 0.76 | SERPINE1 (0.41) | SERPINE1KMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL23571733 | 0.74 | MEN1 (0.47) | KMT2AMEN1NPC1ALDH1A1MAPT | |
| SCHEMBL13144722 | 0.72 | CA5A (0.50) | SERPINE1KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL3353646 | 0.72 | CA12 (0.70) | ALDH1A1MAPTKDM4ELMNATDP1 | |
| SCHEMBL9768021 | 0.72 | KMT2A (0.39) | KMT2AMEN1NPC1ALDH1A1MAPT | |
| SCHEMBL16478409 | 0.72 | GAA (0.52) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL20199381 | 0.71 | SERPINE1 (0.49) | SERPINE1KDM4ELMNATDP1FUT7 | |
| SCHEMBL16281799 | 0.71 | PTPN11 (0.45) | SERPINE1KMT2AMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013089-A1 | MACROCYCLIC POLYETHER CARBOXYLIC ACIDS | URBAN FRANK J (US) | 1993-07-08 | — | — | WO | disclosed |
| US-4935442-A | Tetrahydrofuran-containing macrocyclic polyether carboxylic acids | PFIZER INC. (US) | 1990-06-19 | — | — | US | disclosed |
| US-4876367-A | ANIMAL GROWTH REGULATORS | PFIZER INC. (US) | 1989-10-24 | — | — | US | disclosed |
| US-4777270-A | INCREASE EFFICIENCY OF FEED UTILIZATION IN RUMINANTS | PFIZER INC. (US) | 1988-10-11 | — | — | US | disclosed |