Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 7/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | XDH | P47989 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 4/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | POLA1 | P09884 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL39049 | 0.89 | POLB (0.61) | SERPINE1POLBKDM4ELMNAGAA | |
| SCHEMBL13243342 | 0.83 | SERPINE1 (0.44) | SERPINE1POLBKDM4ELMNAGAA | |
| SCHEMBL1174843 | 0.81 | ESR1 (0.46) | SERPINE1ESR1CA12CA1CA2 | |
| SCHEMBL13243341 | 0.81 | PTGS2 (0.61) | SERPINE1POLBKDM4ELMNAGAA | |
| SCHEMBL31588013 | 0.80 | SHBG (0.45) | SERPINE1POLBKDM4ELMNAGAA | |
| SCHEMBL31588038 | 0.80 | SHBG (0.45) | SERPINE1POLBKDM4ELMNAGAA | |
| SCHEMBL3353446 | 0.79 | LMNA (0.77) | SERPINE1POLBKDM4ELMNAGAA | |
| SCHEMBL1570461 | 0.79 | CA12 (0.47) | KDM4ELMNAXDHTDP1ESR1 | |
| SCHEMBL17184949 | 0.79 | CA12 (0.47) | SERPINE1XDHCA12CA1CA2 | |
| SCHEMBL7058435 | 0.78 | CA12 (0.47) | SERPINE1POLBKDM4ELMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180147326-A1 | Antifouling Polymeric Coating Compositions | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2018-05-31 | — | — | US | disclosed |