Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATIC | P31939 | 1/20 | 0.44 |
| ▸ | SHBG | P04278 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 7/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.39 |
| ▸ | SERPINA6 | P08185 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.39 |
| ▸ | SNCA | P37840 | 4/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.39 |
| ▸ | PGR | P06401 | 3/20 | 0.39 |
| ▸ | AR | P10275 | 3/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.39 |
| ▸ | CYP51A1 | Q16850 | 2/20 | 0.39 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9542430 | 0.80 | SHBG (0.45) | ATICSHBGLMNAHSD17B10SERPINA6 | |
| SCHEMBL9542789 | 0.77 | SHBG (0.62) | ATICSHBGLMNAHSD17B10SERPINA6 | |
| SCHEMBL9542595 | 0.74 | SHBG (0.47) | ATICSHBGLMNAHSD17B10SERPINA6 | |
| SCHEMBL9542813 | 0.71 | SHBG (0.46) | ATICSHBGLMNAHSD17B10SERPINA6 | |
| SCHEMBL3748874 | 0.69 | SHBG (0.42) | SHBGLMNAHSD17B10SERPINA6TSHR | |
| SCHEMBL3748877 | 0.69 | SHBG (0.42) | SHBGLMNAHSD17B10SERPINA6TSHR | |
| SCHEMBL9544741 | 0.69 | SHBG (0.44) | ATICSHBGLMNAHSD17B10SERPINA6 | |
| SCHEMBL9596200 | 0.65 | LMNA (0.41) | SHBGLMNAHSD17B10SERPINA6TSHR | |
| SCHEMBL3749413 | 0.65 | SHBG (0.57) | SHBGLMNAHSD17B10SERPINA6TSHR | |
| SCHEMBL3752458 | 0.65 | SHBG (0.57) | SHBGLMNAHSD17B10SERPINA6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013122-A1 | 3-METHYLSULPHONYLHYDRAZONO AND 3-OXYIMINO STEROIDS, A METHOD OF PREPARING THEM, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND THEIR USE IN THE PREPARATION OF DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-07-08 | — | — | WO | disclosed |