SCHEMBL954276

SCHEMBL954276

Nc1c(I)cc(I)cc1C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.44
MAOB P27338 1/20 0.43
PTPN1 P18031 2/20 0.38
PTPRC P08575 1/20 0.38
PTPN2 P17706 1/20 0.38
PTPRA P18433 1/20 0.38
PTPRB P23467 1/20 0.38
PTPRE P23469 1/20 0.38
PTPN6 P29350 1/20 0.38
KMT2A Q03164 5/20 0.38
GFER P55789 1/20 0.38
RXFP1 Q9HBX9 1/20 0.38
TTR P02766 1/20 0.37
TPMT P51580 1/20 0.37
MAPT P10636 4/20 0.36
MEN1 O00255 4/20 0.36
THRB P10828 3/20 0.36
TDP1 Q9NUW8 3/20 0.36
CYP3A4 P08684 3/20 0.36
ALDH1A1 P00352 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1462336 0.89 KDM4E (0.48) KDM4EMAOBPTPN1PTPRCPTPN2
SCHEMBL2954701 0.81 CASP7 (0.48) KDM4EMAOBPTPN1PTPRCPTPN2
SCHEMBL958617 0.79 KDM4E (0.41) KDM4EPTPN1PTPRCPTPN2PTPRA
SCHEMBL7821086 0.79 KDM4E (0.41) KDM4EMAOBPTPN1PTPRCPTPN2
SCHEMBL3564724 0.79 KDM4E (0.41) KDM4EPTPN1PTPRCPTPN2PTPRA
SCHEMBL857080 0.79 KDM4E (0.66) KDM4EPTPN1PTPRCPTPN2PTPRA
SCHEMBL5755662 0.79 KEAP1 (0.50) KDM4EPTPN1KMT2AGFERRXFP1
SCHEMBL951022 0.79 CYP3A4 (0.55) KDM4EKMT2ATPMTMAPTMEN1
SCHEMBL17873477 0.79 KDM4E (0.50) KDM4EKMT2AGFERRXFP1TPMT
SCHEMBL30625240 0.79 KDM4E (0.66) KDM4EKMT2AGFERRXFP1TTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118184679-A Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material 中国石油天然气股份有限公司 2024-06-14 CN claimed
US-6756486-B1 LAKED DISAZO YELLOW PIGMENTS HAVING DESIRABLE GREEN SHADE, HEAT STABILITY, GOOD STRENGTH, BLEED RESISTANCE, MIGRATION RESISTANCE, AND LOW OR NO TOXICITY ENGELHARD CORPORATION 2004-06-29 US claimed
WO-2026100524-A1 RADIATION-SENSITIVE COMPOSITION, PATTERN FORMING METHOD, ONIUM SALT COMPOUND, AND POLYMER JSR株式会社 2026-05-15 WO disclosed
WO-2025004967-A1 RESIST COMPOSITION, RESIST PATTERN FORMATION METHOD, COMPOUND, AND POLYMER COMPOUND 東京応化工業株式会社 2025-01-02 WO disclosed
WO-2024176701-A1 RESIST COMPOSITION, RESIST PATTERN FORMATION METHOD, COMPOUND, AND POLYMER COMPOUND 東京応化工業株式会社 2024-08-29 WO disclosed
WO-2024127977-A1 RESIST COMPOSITION, RESIST PATTERN FORMATION METHOD, COMPOUND, AND ACID DIFFUSION CONTROL AGENT 東京応化工業株式会社 2024-06-20 WO disclosed
CN-118184679-A Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material 中国石油天然气股份有限公司 2024-06-14 CN disclosed
WO-2024122425-A1 RESIST COMPOSITION, RESIST PATTERN FORMATION METHOD, COMPOUND, AND ACID DIFFUSION CONTROL AGENT 東京応化工業株式会社 2024-06-13 WO disclosed
US-11835859-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-12-05 US disclosed
US-11835859-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-12-05 US disclosed
US-20230384676-A1 RADIATION-SENSITIVE RESIN COMPOSITION, METHOD OF FORMING PATTERN, POLYMER, AND COMPOUND JSR CORPORATION (JP) 2023-11-30 US disclosed
US-6066638-A CONTROLLING PLANT DISEASES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2000-05-23 US disclosed
WO-2000001692-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2000-01-13 WO disclosed
EP-0560722-B1 Chromogenic lactam compounds, their production and use CIBA SC HOLDING AG (CH) 1999-11-17 EP disclosed
EP-0694809-B1 A novel class of grain growth modifiers for the preparation of high chloride (111) tabular grain emulsions (II) EASTMAN KODAK CO (US) 1999-10-06 EP disclosed
EP-0836602-A1 FUNGICIDAL PYRIMIDINONES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1998-04-22 EP disclosed
WO-1997002262-A1 FUNGICIDAL PYRIMIDINONES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-01-23 WO disclosed
US-5362872-A Used in pressure sensitive or heat sensitive recording CIBA-GEIGY CORPORATION (US) 1994-11-08 US disclosed
EP-0560722-A1 Chromogenic lactam compounds, their production and use CIBA-GEIGY AG (CH) 1993-09-15 EP disclosed
US-4172098-A REACTION OF A HALOAMINOBENZOIC ACID WITH AN ALCOHOL AND NITROSYLATING AGENT IN THE PRESCENCE OF AN ACID AND WATER BASF AKTIENGESELLSCHAFT (DE) 1979-10-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230384676-A1 RADIATION-SENSITIVE RESIN COMPOSITION, METHOD OF FORMING PATTERN, POLYMER, AND COMPOUND RER1, RFT1, RAD51 KDM4E 1445/4885MAOB 3559/4885PTPN1 4336/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.