Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 2/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.49 |
| ▸ | DRD2 | P14416 | 3/20 | 0.48 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.46 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27679079 | 0.87 | CHRM4 (0.43) | ROCK2CHRM4DRD2DRD4 | |
| SCHEMBL7981628 | 0.85 | CHRM4 (0.53) | CHRM4DRD2NPFFR1NPFFR2KMT2A | |
| SCHEMBL3509882 | 0.83 | BRD4 (0.48) | ROCK2L3MBTL1 | |
| SCHEMBL30531024 | 0.83 | BRD4 (0.48) | ROCK2L3MBTL1 | |
| SCHEMBL15866724 | 0.83 | ACHE (0.49) | — | |
| SCHEMBL13830591 | 0.82 | QDPR (0.45) | ROCK2CHRM4 | |
| SCHEMBL25358558 | 0.81 | GLS (0.48) | ROCK2KMT2AL3MBTL1 | |
| SCHEMBL30531063 | 0.81 | GLS (0.48) | ROCK2KMT2AL3MBTL1 | |
| SCHEMBL25048390 | 0.81 | BRD4 (0.47) | ROCK2KMT2AL3MBTL1 | |
| SCHEMBL7766536 | 0.81 | DRD4 (0.69) | DRD2KMT2ADRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993016077-A1 | 7-SUBSTITUTED QUINOLONES AND NAPHTHYRIDONES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1993-08-19 | — | — | WO | disclosed |