Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9542124 | 0.83 | MAPT (0.42) | ALDH1A1MAPTGAAMDM2SMN1; SMN2 | |
| SCHEMBL1026028 | 0.82 | MAPT (0.41) | ALDH1A1MAPTGAAMDM2SMN1; SMN2 | |
| SCHEMBL8803147 | 0.76 | MAPT (0.46) | ALDH1A1MAPTGAAMDM2SMN1; SMN2 | |
| SCHEMBL3469591 | 0.74 | MAPT (0.49) | ALDH1A1MAPTGAAMDM2SMN1; SMN2 | |
| SCHEMBL8594839 | 0.74 | ALDH1A1 (0.46) | ALDH1A1MAPTGAAMDM2SMN1; SMN2 | |
| SCHEMBL4269080 | 0.74 | MAPT (0.49) | ALDH1A1MAPTGAAMDM2SMN1; SMN2 | |
| SCHEMBL9542100 | 0.73 | ALDH1A1 (0.43) | ALDH1A1MAPTGAAMDM2SMN1; SMN2 | |
| SCHEMBL7801786 | 0.72 | ALDH1A1 (0.45) | ALDH1A1MAPTGAAMDM2SMN1; SMN2 | |
| SCHEMBL3986231 | 0.72 | MAPT (0.47) | ALDH1A1MAPTGAAMDM2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4618823 | 0.72 | MAPT (0.47) | ALDH1A1MAPTGAAMDM2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993020817-A1 | NOVEL USE OF NITROIMIDAZOLES | HYDRO PHARMA SVERIGE AB (SE) | 1993-10-28 | — | — | WO | disclosed |