Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | PRKCI | P41743 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | GRK5 | P34947 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9542979 | 0.84 | GRK5 (0.47) | HTR2BKDM4EMEN1TP53CYP1A2 | |
| SCHEMBL7403640 | 0.82 | HTR2B (0.44) | HTR2BKDM4EMEN1TP53CYP1A2 | |
| SCHEMBL27469254 | 0.81 | HTR2B (0.40) | HTR2BKDM4EMEN1TP53CYP1A2 | |
| SCHEMBL27407225 | 0.81 | HTR2B (0.39) | HTR2BKDM4EMEN1TP53CYP1A2 | |
| SCHEMBL27384172 | 0.81 | NOTUM (0.39) | HTR2BKDM4EMEN1TP53CYP1A2 | |
| SCHEMBL9545059 | 0.80 | GRM4 (0.39) | HTR2BKDM4EMEN1TP53CYP1A2 | |
| Hydrochloric Acid SCHEMBL27407226 | 0.80 | HTR2C (0.40) | HTR2BKDM4EMEN1TP53CYP1A2 | |
| SCHEMBL18962969 | 0.79 | MAPT (0.52) | HTR2BKDM4EMEN1TP53CYP1A2 | |
| SCHEMBL9544220 | 0.78 | HTR2B (0.47) | HTR2BKDM4EMEN1TP53CYP1A2 | |
| SCHEMBL7098140 | 0.78 | HTR2B (0.42) | HTR2BKDM4EMEN1TP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993016694-A1 | USE OF INDYLPYRIDYLUREAS TO HEAL THE EFFECTS OF BRAIN OR SPIRAL TRAUMA | SMITHKLINE BEECHAM PLC (GB) | 1993-09-02 | — | — | WO | claimed |
| WO-1993016694-A1 | USE OF INDYLPYRIDYLUREAS TO HEAL THE EFFECTS OF BRAIN OR SPIRAL TRAUMA | SMITHKLINE BEECHAM PLC (GB) | 1993-09-02 | — | — | WO | disclosed |