Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8925930 | 0.83 | KMT2A (0.60) | KMT2ALMNAMEN1PTGS1PTGS2 | |
| SCHEMBL10931910 | 0.82 | RAB9A (0.45) | KMT2AMEN1ALDH1A1TSHRMAPK1 | |
| SCHEMBL5789506 | 0.81 | KMT2A (0.62) | KMT2ALMNAMEN1PTGS1PTGS2 | |
| SCHEMBL6874324 | 0.81 | KMT2A (0.62) | KMT2ALMNAMEN1PTGS1PTGS2 | |
| SCHEMBL8634836 | 0.81 | KMT2A (0.62) | KMT2ALMNAMEN1PTGS1PTGS2 | |
| SCHEMBL8571791 | 0.81 | KMT2A (0.62) | KMT2ALMNAMEN1PTGS1PTGS2 | |
| SCHEMBL7626977 | 0.81 | KMT2A (0.53) | KMT2ALMNAMEN1PTGS1PTGS2 | |
| SCHEMBL28772271 | 0.80 | KMT2A (0.56) | KMT2ALMNAMEN1PTGS1PTGS2 | |
| SCHEMBL6945331 | 0.80 | KMT2A (0.56) | KMT2ALMNAMEN1PTGS1PTGS2 | |
| SCHEMBL6945334 | 0.80 | KMT2A (0.56) | KMT2ALMNAMEN1PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993010076-A1 | SYNTHESIS AND OPTICAL RESOLUTION OF THE TAXOL SIDE CHAIN AND RELATED COMPOUNDS | THE UNIVERSITY OF MISSISSIPPI (US) | 1993-05-27 | — | — | WO | claimed |
| WO-1993010076-A1 | SYNTHESIS AND OPTICAL RESOLUTION OF THE TAXOL SIDE CHAIN AND RELATED COMPOUNDS | THE UNIVERSITY OF MISSISSIPPI (US) | 1993-05-27 | — | — | WO | disclosed |