Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SLC6A9 | P48067 | 7/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9586388 | 0.82 | MEN1 (0.47) | MEN1KMT2ASLC6A9HSD11B1THRB | |
| SCHEMBL9541762 | 0.81 | MEN1 (0.48) | MEN1KMT2ASLC6A9HSD11B1THRB | |
| SCHEMBL9542190 | 0.77 | MEN1 (0.44) | MEN1KMT2ASLC6A9HSD11B1THRB | |
| SCHEMBL9542171 | 0.77 | GAA (0.46) | MEN1KMT2ASLC6A9THRBMAPT | |
| SCHEMBL10721820 | 0.77 | HSD11B1 (0.57) | SLC6A9HSD11B1THRBTHRA | |
| SCHEMBL9543490 | 0.76 | MEN1 (0.51) | MEN1KMT2AHSD11B1THRBTHRA | |
| SCHEMBL27811000 | 0.75 | AGER (0.52) | MEN1KMT2AHSD11B1THRBTHRA | |
| SCHEMBL11711681 | 0.74 | MEN1 (0.65) | MEN1KMT2AHSD11B1THRBTSHR | |
| SCHEMBL4557404 | 0.73 | AGER (0.50) | MEN1KMT2AHSD11B1 | |
| SCHEMBL10722512 | 0.72 | HSD11B1 (0.56) | MEN1KMT2ASLC6A9HSD11B1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5223539-A | Antagonist of platelet activating factor | G. D. SEARLE & CO. (US) | 1993-06-29 | — | — | US | disclosed |
| WO-1993010077-A1 | N,N-DI-ALKYL(PHENOXY)BENZAMIDE DERIVATIVES | G.D. SEARLE & CO. (US) | 1993-05-27 | — | — | WO | disclosed |