Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.40 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9543503 | 0.82 | MEN1 (0.45) | MEN1KMT2ATSHRTP53SLC6A9 | |
| SCHEMBL9542205 | 0.81 | TSHR (0.43) | MEN1KMT2ATSHRTP53HTT | |
| SCHEMBL9543471 | 0.79 | MEN1 (0.42) | MEN1KMT2ATSHRNPSR1SLC6A4 | |
| SCHEMBL11711681 | 0.78 | MEN1 (0.65) | MEN1KMT2ATSHRL3MBTL1ALDH1A1 | |
| SCHEMBL9540778 | 0.77 | MEN1 (0.43) | MEN1KMT2ATSHRTP53HTT | |
| SCHEMBL10722512 | 0.76 | HSD11B1 (0.56) | MEN1KMT2ASLC6A4KCNH2L3MBTL1 | |
| SCHEMBL9541762 | 0.74 | MEN1 (0.48) | MEN1KMT2ATSHRTP53HTT | |
| SCHEMBL10724251 | 0.73 | SLC6A4 (0.56) | MEN1KMT2ASLC6A4KCNH2L3MBTL1 | |
| SCHEMBL9541782 | 0.73 | KMT2A (0.41) | MEN1KMT2ATSHRTP53HTT | |
| SCHEMBL9542243 | 0.73 | POLB (0.46) | MEN1KMT2ATSHRNPSR1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5223539-A | Antagonist of platelet activating factor | G. D. SEARLE & CO. (US) | 1993-06-29 | — | — | US | claimed |