Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | LSS | P48449 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9543520 | 0.81 | TSHR (0.51) | TSHRAKT1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL176484 | 0.79 | TSHR (0.53) | TSHRAKT1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL11184042 | 0.79 | TSHR (0.53) | TSHRAKT1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL10296224 | 0.78 | GSK3B (0.45) | TSHRKDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL12650288 | 0.78 | ALDH1A1 (0.53) | KDM4EMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL14493279 | 0.78 | ALDH1A1 (0.42) | TSHRKDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL8588107 | 0.78 | TSHR (0.51) | TSHRAKT1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL8673185 | 0.78 | HSD11B1 (0.51) | TSHRKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL9474105 | 0.77 | TSHR (0.48) | TSHRAKT1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8719506 | 0.76 | TSHR (0.50) | TSHRAKT1KDM4ESMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5223539-A | Antagonist of platelet activating factor | G. D. SEARLE & CO. (US) | 1993-06-29 | — | — | US | disclosed |
| WO-1993010077-A1 | N,N-DI-ALKYL(PHENOXY)BENZAMIDE DERIVATIVES | G.D. SEARLE & CO. (US) | 1993-05-27 | — | — | WO | disclosed |