Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.34 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9543419 | 0.88 | HDAC8 (0.35) | HDAC8MEN1KMT2AUCHL1FFAR2 | |
| SCHEMBL9542843 | 0.88 | ABCB1 (0.37) | HDAC8MEN1KMT2AABCB1UCHL1 | |
| SCHEMBL9543806 | 0.82 | HDAC8 (0.40) | HDAC8MEN1KMT2AUCHL1PTPN1 | |
| SCHEMBL9544061 | 0.77 | HDAC8 (0.33) | HDAC8UCHL1 | |
| SCHEMBL475745 | 0.76 | FFAR2 (0.51) | ABCB1RIPK1FFAR2 | |
| SCHEMBL859599 | 0.76 | FFAR2 (0.51) | ABCB1RIPK1FFAR2 | |
| SCHEMBL6183606 | 0.76 | FFAR2 (0.51) | ABCB1RIPK1FFAR2 | |
| SCHEMBL2896922 | 0.76 | FFAR2 (0.51) | ABCB1RIPK1FFAR2 | |
| SCHEMBL5156869 | 0.76 | FFAR2 (0.51) | ABCB1RIPK1FFAR2 | |
| SCHEMBL29040317 | 0.76 | FFAR2 (0.51) | ABCB1RIPK1FFAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993020099-A2 | CCK AND/OR GASTRIN RECEPTOR LIGANDS | FERRING B.V. (NL) | 1993-10-14 | — | — | WO | disclosed |