Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | CCKBR | P32239 | 1/20 | 0.33 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.32 |
| ▸ | ACE | P12821 | 3/20 | 0.31 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9543419 | 0.90 | HDAC8 (0.35) | HDAC8CCKBRUCHL1 | |
| SCHEMBL9542843 | 0.88 | ABCB1 (0.37) | HDAC8CCKBRUCHL1NR1D1 | |
| SCHEMBL2038282 | 0.79 | FFAR2 (0.44) | ACE | |
| SCHEMBL29788213 | 0.79 | FFAR2 (0.44) | ACE | |
| SCHEMBL9544057 | 0.79 | FFAR2 (0.44) | ACE | |
| SCHEMBL9544302 | 0.79 | FFAR2 (0.44) | ACE | |
| SCHEMBL2039149 | 0.78 | TYMS (0.41) | NR1D1 | |
| SCHEMBL9543877 | 0.77 | NR1D1 (0.37) | HDAC8CCKBRNR1D1 | |
| SCHEMBL9543527 | 0.77 | HDAC8 (0.38) | HDAC8UCHL1 | |
| SCHEMBL9542557 | 0.76 | LIPG (0.33) | HDAC8ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993020099-A2 | CCK AND/OR GASTRIN RECEPTOR LIGANDS | FERRING B.V. (NL) | 1993-10-14 | — | — | WO | claimed |
| WO-1993020099-A2 | CCK AND/OR GASTRIN RECEPTOR LIGANDS | FERRING B.V. (NL) | 1993-10-14 | — | — | WO | disclosed |