Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MT-CO2 | P00403 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9064206 | 0.88 | MT-CO2 (0.45) | MT-CO2PTGS1PTGS2ALDH1A1LMNA | |
| SCHEMBL27313584 | 0.87 | MT-CO2 (0.44) | MT-CO2PTGS1PTGS2ALDH1A1LMNA | |
| SCHEMBL9558290 | 0.85 | ALDH1A1 (0.43) | MT-CO2PTGS1PTGS2ALDH1A1HTT | |
| SCHEMBL27314658 | 0.84 | MT-CO2 (0.42) | MT-CO2PTGS1PTGS2PSEN1PSEN2 | |
| SCHEMBL1626214 | 0.82 | SLC6A3 (0.57) | MT-CO2PTGS1PTGS2ALDH1A1LMNA | |
| SCHEMBL17831730 | 0.82 | MT-CO2 (0.40) | MT-CO2PTGS1PTGS2PSEN1PSEN2 | |
| SCHEMBL17891807 | 0.80 | MT-CO2 (0.55) | MT-CO2PTGS1PTGS2ALDH1A1LMNA | |
| SCHEMBL9063569 | 0.80 | MT-CO2 (0.55) | MT-CO2PTGS1PTGS2ALDH1A1LMNA | |
| SCHEMBL10931210 | 0.78 | MT-CO2 (0.47) | MT-CO2PTGS1PTGS2ALDH1A1PSEN1 | |
| SCHEMBL29749568 | 0.78 | MT-CO2 (0.47) | MT-CO2PTGS1PTGS2ALDH1A1PSEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5260277-A | Cell receptor antagonists | TANABE SEIYAKU CO., LTD. (JP) | 1993-11-09 | — | — | US | disclosed |
| WO-1993008823-A1 | GUANIDINYL AND RELATED CELL ADHESION MODULATION COMPOUNDS | TANABE SEIYAKU CO., LTD. (JP) | 1993-05-13 | — | — | WO | disclosed |