Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 8/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | EDNRB | P24530 | 7/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7814457 | 0.82 | EDNRA (0.50) | EDNRAEDNRB | |
| SCHEMBL9543742 | 0.81 | EDNRA (0.49) | EDNRAEDNRB | |
| SCHEMBL9543747 | 0.76 | EDNRA (0.48) | EDNRAEDNRB | |
| SCHEMBL7653814 | 0.73 | EDNRA (0.41) | EDNRAMAOBEDNRB | |
| SCHEMBL6953835 | 0.72 | EDNRA (0.45) | EDNRAEDNRB | |
| SCHEMBL8294440 | 0.71 | MAOB (0.47) | EDNRAMAOBEDNRB | |
| SCHEMBL7651503 | 0.70 | EDNRA (0.50) | EDNRAEDNRB | |
| SCHEMBL7651495 | 0.70 | EDNRA (0.50) | EDNRAEDNRB | |
| SCHEMBL7653068 | 0.70 | EDNRA (0.51) | EDNRAEDNRB | |
| SCHEMBL8626955 | 0.70 | CYP3A4 (0.42) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929106-A | VASODILATOR; HYPOTENSIVE AGENT | SMITHKLINE BEECHAM CORPORATION (US) | 1999-07-27 | — | — | US | disclosed |
| US-5736564-A | DIHYDROISOINDOLE DERIVATIVES | SMITHKLINE BEECHAM CORPORATION (US) | 1998-04-07 | — | — | US | disclosed |