Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 2/20 | 0.39 |
| ▸ | RORA | P35398 | 2/20 | 0.39 |
| ▸ | RORC | P51449 | 2/20 | 0.39 |
| ▸ | RORB | Q92753 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7410652 | 0.81 | MAPT (0.42) | ALDH1A1KDM4EPOLBHPGDSMN1; SMN2 | |
| SCHEMBL9541405 | 0.79 | PPARG (0.53) | ALDH1A1KDM4EHPGDHSD17B10CYP1A2 | |
| SCHEMBL9539844 | 0.79 | PDE3B (0.37) | LMNAHSD17B10GAANPC1PDE3B | |
| SCHEMBL9540684 | 0.75 | SLC33A1 (0.39) | — | |
| SCHEMBL7412913 | 0.74 | THRB (0.47) | ALDH1A1KDM4EPOLBHPGDPGR | |
| SCHEMBL8801906 | 0.73 | CNR2 (0.46) | LMNAKDM4EPOLBHPGDSMN1; SMN2 | |
| SCHEMBL7415589 | 0.72 | TP53 (0.44) | LMNAPOLBSMN1; SMN2TP53MAPT | |
| SCHEMBL7260919 | 0.72 | KDM4E (0.48) | ALDH1A1LMNAKDM4EPOLBHPGD | |
| SCHEMBL8803243 | 0.72 | CNR2 (0.46) | LMNAKDM4EPOLBHPGDSMN1; SMN2 | |
| SCHEMBL7409597 | 0.72 | CNR2 (0.46) | LMNAKDM4EPOLBHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993014086-A1 | SUBSTITUTED 1-ISOQUINOLONE DERIVATIVES AS ANGIOTENSIN II ANTAGONISTS | SYNTEX (U.S.A.) INC. (US) | 1993-07-22 | — | — | WO | disclosed |