Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | GALK1 | P51570 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9542481 | 0.80 | HSD17B10 (0.37) | KMT2AMEN1GAAPKMCASP1 | |
| SCHEMBL9542478 | 0.80 | HSD17B10 (0.37) | KMT2AMEN1GAAPKMCASP1 | |
| SCHEMBL9543780 | 0.79 | ALDH1A1 (0.41) | PDE3BPDE3AKMT2ANPC1RAB9A | |
| SCHEMBL9542612 | 0.75 | MAPT (0.40) | LMNASMN1; SMN2GAA | |
| SCHEMBL9542616 | 0.75 | MAPT (0.40) | LMNASMN1; SMN2GAA | |
| SCHEMBL9541340 | 0.72 | PDE3B (0.37) | PDE3BPDE3AKMT2AMEN1GAA | |
| SCHEMBL9539925 | 0.69 | KMT2A (0.37) | KMT2ANPC1RAB9AMEN1LMNA | |
| SCHEMBL9539919 | 0.69 | KMT2A (0.37) | KMT2ANPC1RAB9AMEN1LMNA | |
| SCHEMBL8801682 | 0.68 | SLC5A2 (0.44) | KMT2A | |
| SCHEMBL9541398 | 0.67 | VKORC1 (0.34) | PDE3BPDE3AVKORC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993014086-A1 | SUBSTITUTED 1-ISOQUINOLONE DERIVATIVES AS ANGIOTENSIN II ANTAGONISTS | SYNTEX (U.S.A.) INC. (US) | 1993-07-22 | — | — | WO | disclosed |