Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | ALDH1A2 | O94788 | 6/20 | 0.52 |
| ▸ | ALDH2 | P05091 | 6/20 | 0.52 |
| ▸ | ALDH3A1 | P30838 | 6/20 | 0.52 |
| ▸ | ALDH1A3 | P47895 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9539942 | 0.87 | HTR3E (0.47) | ALDH1A1KMT2AMEN1HIF1ANPC1 | |
| SCHEMBL8561156 | 0.86 | ALDH1A1 (0.42) | ALDH1A1ALDH1A2ALDH2ALDH3A1ALDH1A3 | |
| SCHEMBL8561759 | 0.82 | ALDH1A1 (0.51) | ALDH1A1KMT2AMEN1KDM4ETSHR | |
| SCHEMBL8566268 | 0.81 | ALDH1A1 (0.42) | ALDH1A1KMT2AMEN1KDM4ETSHR | |
| SCHEMBL15568741 | 0.75 | ALDH1A1 (0.63) | ALDH1A1ALDH1A2ALDH2ALDH3A1ALDH1A3 | |
| SCHEMBL9636347 | 0.75 | HTR3E (0.48) | ALDH1A1KMT2AMEN1HIF1ANPC1 | |
| SCHEMBL16824663 | 0.75 | KMT2A (0.50) | ALDH1A1ALDH1A2ALDH2ALDH3A1ALDH1A3 | |
| SCHEMBL8564562 | 0.73 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1KDM4ETSHR | |
| SCHEMBL8565760 | 0.72 | MEN1 (0.48) | ALDH1A1ALDH1A2ALDH2ALDH3A1ALDH1A3 | |
| SCHEMBL28991317 | 0.72 | ALDH1A1 (0.65) | ALDH1A1ALDH1A2ALDH2ALDH3A1ALDH1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993014088-A1 | ANTIHISTAMINIC PIPERAZINYL DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-07-22 | — | — | WO | disclosed |