Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.46 |
| ▸ | CCR3 | P51677 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.42 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.42 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8562045 | 0.88 | PRMT3 (0.41) | GRM2DRD2DRD4DRD3LMNA | |
| SCHEMBL8568859 | 0.87 | DRD2 (0.37) | MEN1KMT2AALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL9537178 | 0.86 | MEN1 (0.50) | MEN1KMT2AALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL5626341 | 0.84 | MEN1 (0.66) | MEN1KMT2AALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL8565529 | 0.83 | GRIN2B (0.38) | MEN1KMT2AALDH1A1GRM2DRD2 | |
| SCHEMBL9535902 | 0.83 | MEN1 (0.63) | MEN1KMT2AALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL9382748 | 0.82 | MEN1 (0.50) | MEN1KMT2AALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL9539854 | 0.82 | ALDH1A1 (0.52) | MEN1KMT2AALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL8561156 | 0.81 | ALDH1A1 (0.42) | ALDH1A1MAPTSMN1; SMN2ALDH1A2ALDH2 | |
| Acetic Acid SCHEMBL9593584 | 0.80 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0539421-B1 | NOVEL OXAZOLYL DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 1998-09-23 | — | — | EP | disclosed |
| US-5278165-A | Oxazolyl imidazol[4,5-b]pyridin and pyrimidine compounds | JANSSEN PHARMACEUTICA N.V. (BE) | 1994-01-11 | — | — | US | disclosed |
| US-5217980-A | Antiallergens | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-06-08 | — | — | US | disclosed |
| WO-1992001687-A1 | NOVEL OXAZOLYL DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-02-06 | — | — | WO | disclosed |