Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9296106 | 0.93 | KDM4E (0.47) | ALDH1A1KDM4EHPGDLMNAL3MBTL1 | |
| SCHEMBL645045 | 0.83 | ADORA3 (0.54) | ALDH1A1KDM4EHPGDRAB9AADORA3 | |
| SCHEMBL15307199 | 0.78 | HPGD (0.39) | ALDH1A1KDM4EHPGDLMNAL3MBTL1 | |
| SCHEMBL15307200 | 0.76 | HPGD (0.48) | ALDH1A1KDM4EHPGDLMNAL3MBTL1 | |
| SCHEMBL15777482 | 0.75 | ADORA2A (0.43) | ALDH1A1KDM4EHPGDLMNARAB9A | |
| SCHEMBL12429213 | 0.75 | ALDH1A1 (0.48) | ALDH1A1KDM4EHPGDRAB9AADORA3 | |
| SCHEMBL24831751 | 0.74 | RAB9A (0.45) | ALDH1A1KDM4EHPGDRAB9AADORA3 | |
| SCHEMBL10564142 | 0.73 | KMT2A (0.43) | ALDH1A1KDM4EHPGDLMNAL3MBTL1 | |
| SCHEMBL27478866 | 0.71 | RAB9A (0.36) | ALDH1A1HPGDL3MBTL1RAB9AADORA3 | |
| SCHEMBL11564068 | 0.71 | F2 (0.52) | ALDH1A1KDM4EHPGDADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993017681-A1 | ANGIOTENSIN II RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 1993-09-16 | — | — | WO | disclosed |