Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1D1 | P20393 | 3/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | CCKBR | P32239 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9542843 | 0.84 | ABCB1 (0.37) | NR1D1HDAC8CCKBRMEN1KMT2A | |
| SCHEMBL9543806 | 0.83 | HDAC8 (0.40) | NR1D1HDAC8KDM4EALDH1A1GLA | |
| SCHEMBL9542557 | 0.73 | LIPG (0.33) | HDAC8 | |
| SCHEMBL9543527 | 0.72 | HDAC8 (0.38) | HDAC8MEN1KMT2A | |
| SCHEMBL27726209 | 0.68 | PTPN1 (0.43) | CYP19A1 | |
| SCHEMBL27705647 | 0.67 | ACE (0.46) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9544896 | 0.65 | FDPS (0.42) | KDM4EALDH1A1GAAMAPTFDPS | |
| SCHEMBL9515381 | 0.64 | EPHX2 (0.41) | GAAMEN1KMT2A | |
| SCHEMBL9515374 | 0.64 | EPHX2 (0.41) | GAAMEN1KMT2A | |
| SCHEMBL9515367 | 0.64 | EPHX2 (0.41) | GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993020099-A2 | CCK AND/OR GASTRIN RECEPTOR LIGANDS | FERRING B.V. (NL) | 1993-10-14 | — | — | WO | disclosed |