Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 7/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 1/20 | 0.35 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9544811 | 0.86 | ELANE (0.51) | ELANEHTRA1CMA1APP | |
| SCHEMBL9544288 | 0.85 | CXCR3 (0.41) | CMA1ATM | |
| SCHEMBL9543947 | 0.83 | KMT2A (0.45) | ELANEHTRA1CMA1ATMKMT2A | |
| SCHEMBL9543950 | 0.83 | KMT2A (0.45) | ELANEHTRA1CMA1ATMKMT2A | |
| SCHEMBL9542465 | 0.78 | GRIN2B (0.43) | KMT2A | |
| SCHEMBL9545331 | 0.78 | APP (0.40) | ATMAPP | |
| SCHEMBL9544889 | 0.76 | ACE (0.52) | — | |
| SCHEMBL9544378 | 0.75 | FNTA (0.46) | ELANECMA1KMT2ACTSL | |
| SCHEMBL9544383 | 0.75 | FNTA (0.46) | ELANECMA1KMT2ACTSL | |
| SCHEMBL9544087 | 0.75 | HTRA1 (0.49) | HTRA1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993020099-A2 | CCK AND/OR GASTRIN RECEPTOR LIGANDS | FERRING B.V. (NL) | 1993-10-14 | — | — | WO | disclosed |